Anti-SH2D1A抗體,信號傳導T淋巴細胞活化相關蛋白抗體*，在上海研盟生物，我們堅持對產品質量作不斷的評估、創新和改善以確保您對我們產品的高度信任！抗體應用于WB、IHC、IF、ELISA等實驗中，*，提供完善的售前、售中、售后服務！咨詢或在線客服！我們將竭誠為您服務！
背景介紹：SH2D1A, also SH2 domain protein 1A, SAP and CD150/SLAM (signaling lymphocyte activation molecule)-associated protein, influences signaling pathways involving SLAM molecules at the interface between T and B cells. SH2D1A modulates SLAM by blocking the recruitment of tyrosine phosphatase SHP2 to the phosphorylated cytoplasmic domain of SLAM. SLAM activation mediates expansion of activated T cells during immune responses, induces production of interferon-?and changes the functional profile of subsets of T cells. SH2D1A is a hydrophilic, 128 amino acid protein that is 96% homologous to the mouse protein in both SH2 and tail domains. SH2D1A is present in all major subsets of T cells, including CD4+, CD45RO+, CD45RA+ and CD8+, but not in B cells. SH2D1A can interact via an SH2 domain with a motif (TIYXXV) present in the cytoplasmic tail of cell-surface receptors SLAM (CD150), CD84, CD229 (LY9) and CD244 (2B4).
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英文名稱 SH2D1A
抗體名稱 Anti-SH2D1A抗體,信號傳導T淋巴細胞活化相關蛋白抗體
別 名 SH2 domain protein 1A; DSHP; Duncan disease SH2 protein; SAP; Signaling lymphocyte activation molecule associated protein; SLAM associated protein; T cell signal transduction molecule SAP; SH21A_HUMAN.
研究領域 心血管 免疫學 信號轉導
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
細胞定位 細胞漿
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SH2D1A/SAP
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
本公司另供應“信號傳導T淋巴細胞活化相關蛋白抗體”的標記有：Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647 AP APC Biotin Cy3 Cy5 Cy5.5 Cy7 FITC Gold HRP PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 RBITC.
產品規格：100ug/200ug
產品濃度： 1mg/1ml
抗體來源：兔源、鼠源、山羊
克 隆：單克隆抗體、多克隆抗體
抗體類型：一抗
性 狀： 凍干粉或液體
保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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運輸方面：現貨供應，一般為快遞運輸，江浙滬隔天到，外地及偏遠地方三至五天時間到貨
